Brain & development
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Brain & development · Jan 2021
Administration of nusinersen via paramedian approach for spinal muscular atrophy.
To assess the success rate, procedure time, and adverse events of intrathecal administration of nusinersen via the paramedian approach in adolescents and adults with spinal muscular atrophy (SMA) associated with scoliosis. ⋯ Intrathecal administration of nusinersen via the paramedian approach had the advantages of a high success rate and short procedure time with fewer adverse events in SMA patients associated with scoliosis.
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Brain & development · Jan 2021
The changes in the topological properties of brain structural network based on diffusion tensor imaging in pediatric epilepsy patients with vagus nerve stimulators: A graph theoretical analysis.
This study aimed to analyze the topological characteristics of brain structural network in pediatric epilepsy patients with vagus nerve stimulation (VNS) by applying graph theoretical approaches. ⋯ VNS causes topological characteristics changes in pediatric patients with generalized seizures through regulating regional properties in some brain structures.