Journal of epidemiology and community health
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J Epidemiol Community Health · Jun 2015
Meta AnalysisPulmonary function as a risk factor for dementia death: an individual participant meta-analysis of six UK general population cohort studies.
In addition to being associated with all-cause mortality and cardiovascular disease mortality, lung function has been linked with dementia. However, existing studies typically provide imprecise estimates due to small numbers of outcome events and are based on unrepresentative samples of the general population. ⋯ In these general population samples, the relation between three measures of lung function and dementia death followed a dose-response gradient. Being in the bottom quartile of lung function was associated with a doubling of the risk.