Journal of clinical gastroenterology
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J. Clin. Gastroenterol. · Sep 2016
Management of Patients With Pancreatic Cysts: Analysis of Possible False-Negative Cases of Malignancy.
To examine the utility of integrated molecular pathology (IMP) in managing surveillance of pancreatic cysts based on outcomes and analysis of false negatives (FNs) from a previously published cohort (n=492). ⋯ Adjunct use of IMP can provide evidence for relaxed surveillance of patients with benign cysts that meet Fukuoka criteria for closer observation or surgery. Although infrequent, FN results with IMP can be associated with EUS-FNA sampling limitations or high-risk clinical circumstances.
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The goal of this study was to evaluate the safety of propofol when used by gastroenterologists in patients who have an inadequate response to standard sedation (narcotics and benzodiazepines). ⋯ Adjunctive propofol administered by gastroenterologist for conscious sedation was not associated with increased incidence of adverse events. It may be of value in patients who do not respond to conventional sedation.
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J. Clin. Gastroenterol. · Sep 2016
Comparative StudyDevelopment and Validation of a Clostridium difficile Health-related Quality-of-Life Questionnaire.
Patients with Clostridium difficile infection (CDI) can experience long-term symptoms and poor quality of life due to the disease. Despite this, a health-related quality of life (HRQOL) instrument specific for patients with CDI does not exist. The aim of this study was to develop and validate a disease-specific instrument to assess HRQOL in patients with CDI. ⋯ The properties of the newly developed Cdiff32 should make it appropriate to assess changes over time in HRQOL in patients with CDI.