Psychiatry research
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Psychiatry research · Sep 2019
Review Meta AnalysisBrexanolone for postpartum depression: A meta-analysis of randomized controlled studies.
To systematically examine the effectiveness, tolerability, and safety of brexanolone infusion in treating postpartum depression (PPD). ⋯ A single brexanolone infusion appears to have ultra-rapid antidepressant effect for PPD, lasting for up to 1 week. The short and long-term therapeutic effect of brexanolone needs to be examined in large-scale RCTs.