Psychiatry research
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Psychiatry research · Dec 2014
Proton magnetic resonance spectroscopy in obsessive-compulsive disorder: evidence for reduced neuronal integrity in the anterior cingulate.
Neuroimaging studies have suggested that dysfunction of the cortico-striatal-thalamo-cortical (CSTC) circuit is a key pathophysiologic feature of obsessive-compulsive disorder (OCD). Several studies using proton magnetic resonance spectroscopy ((1)H MRS) have found abnormal neural metabolite concentrations among OCD patients. The aim of this study was to investigate the metabolic integrity of the anterior cingulate, caudate and putamen in OCD. ⋯ There was a tendency for levels of NAA/Cr to be lower in the caudate and the putamen in patients with OCD compared with healthy controls. NAA/Cr ratios were negatively correlated with the total scores on the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) in the anterior cingulate in patients with OCD. Our results support the significance and biochemical involvement of the anterior cingulate cortex (ACC) in the pathophysiology of OCD.
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Psychiatry research · Dec 2014
Randomized Controlled TrialPost-traumatic psychological changes among survivors of the Lushan earthquake living in the most affected areas.
The primary objective of our study was to investigate both the negative and positive psychological changes following the Lushan earthquake, and to explore the factors associated with psychological changes. Multi-stage random sampling was used to select respondents from Lushan County, Sichuan Province, China. A simplified Chinese version of the short form of Changes in Outlook Questionnaire (CiOQ-S) was used to assess psychological changes in earthquake survivors. ⋯ The factors associated with positive psychological changes included ethnic minority, high level of education, high household income, not injured in the earthquake, not trapped during the earthquake, and having experienced the Wenchuan earthquake. The factors associated with negative psychological changes included female gender, ethnic minority, low household income, history of diseases, injured during the earthquake, and trapped during the earthquake. The current analysis helps expand our knowledge of the negative and positive psychological changes that may occur following an earthquake experience.
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Psychiatry research · Dec 2014
Randomized Controlled TrialOrienting and maintenance of attention to threatening facial expressions in anxiety--an eye movement study.
Cognitive models posit that anxiety disorders stem in part from underlying attentional biases to threat. Consistent with this, studies have found that the attentional bias to threat-related stimuli is greater in high vs. low anxious individuals. Nevertheless, it is not clear if similar biases exist for different threatening emotions or for any facial emotional stimulus. ⋯ Our results for attentional maintenance were not consistent. The results of the present study suggest that attentional processes may be more emotion-specific than previously believed. Our results suggest that attentional processes for different threatening emotions may not be the same and that attentional processes for some negative and some positive emotions may be similar.
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Psychiatry research · Nov 2014
Rapid spread of suicide by charcoal burning from 2007 to 2011 in Korea.
Despite rapid increase of suicide by charcoal burning within 5 years, little is known about the characteristics of charcoal burning suicide in Korea. This study aimed to examine the trends and risk factors in the spread of suicide using this method. We identified an association between media reporting of suicide by charcoal burning and its incidence. ⋯ Internet reports of suicide via charcoal burning tended to precede the increased incidence of suicide using this method, but only during the early period of the suicide epidemic. Our findings suggest that one episode of heavy media coverage of a novel method, such as charcoal burning, is sufficient to increase the prevalence of suicide by that method even after media coverage decreases. These findings are expected to contribute to the prevention of increasing rates of suicide by charcoal burning.
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Apathy is both a symptom and syndrome prevalent in neurodegenerative disease, including motor system disorders, that affects motivation to display goal directed functions. Levy and Dubois (2006) suggested three apathetic subtypes, Cognitive, Emotional-affective and Auto-activation, all with discrete neural correlates and functional impairments. The aim of this study was to create a new apathy measure; the Dimensional Apathy Scale (DAS), which assesses apathetic subtypes and is suitable for use in patient groups with motor dysfunction. 311 healthy participants (mean=37.4, S. ⋯ The subscale items show good internal consistency reliability. A weak to moderate relationship was found with depression using Becks Depression Inventory II. The DAS is a well-constructed method for assessing multidimensional apathy suitable for application to investigate this syndrome in different disease pathologies.