Journal of periodontology
-
Journal of periodontology · Jan 2002
Itraconazole prophylaxis for invasive gingival aspergillosis in neutropenic patients with acute leukemia.
Due to an increasing number of leukemic patients with invasive gingival aspergillosis during neutropenia (neutrophils <500 cells/microl for >10 days), we evaluated the efficacy of oral itraconazole prophylaxis for preventing this invasive infection at our hospital. ⋯ These findings suggest that oral itraconazole could be effective for preventing invasive gingival aspergillosis in neutropenic patients with acute leukemia and warrants further randomized investigation.