Annals of emergency medicine
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Randomized Controlled Trial Comparative Study Clinical Trial
Nasal versus oral midazolam for sedation of anxious children undergoing laceration repair.
To compare the efficacy and safety of a single dose of midazolam, as an oral solution of 0.5 mg/kg, or nasal drops of 0.25 mg/kg, in children undergoing emergency department laceration repair. ⋯ A single dose of oral or nasal midazolam results in reduced anxiety and few complications in selected children undergoing laceration repair in the ED. The oral route was associated with fewer administration problems.
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Randomized Controlled Trial Clinical Trial
Efficacy of rectal midazolam for the sedation of preschool children undergoing laceration repair.
To determine the efficacy of rectal midazolam as sedation for laceration repair in preschool children in the pediatric emergency department. ⋯ Rectal midazolam is an effective method of sedation for facilitating uncomplicated laceration repair in preschool children. However, physicians must be aware of the possibility of paradoxical reactions when using midazolam in children.