International journal of pediatric otorhinolaryngology
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Int. J. Pediatr. Otorhinolaryngol. · Feb 2005
Case ReportsTracheostomy in children with nemaline core myopathy.
Two children with nemaline core myopathy (NM) who required tracheostomy are reported. One had a severe neonatal form requiring tracheostomy in the neonatal period for continuous mechanical ventilation. The other had a milder form with obstructive sleep apnoea, who underwent tracheostomy at age 22 months after adenoidectomy and a trial of nocturnal nasal continuous positive airway pressure ventilation. These cases highlight the clinical heterogeneity of the condition and the important role of the otolaryngologist in its management.
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Int. J. Pediatr. Otorhinolaryngol. · Feb 2005
Treatment results of 59 young patients with nasopharyngeal carcinoma.
To evaluate the outcome of patients =30 years old with non-metastatic nasopharyngeal carcinoma and discover adverse prognostic factors. ⋯ We suggest that RT combined with multiagent chemotherapy is effective in achieving satisfactory DFS and comparable OS in young patients with NPC. Results of both previous series and ours are evoking the necessity of early administration of efficient chemotherapeutic agents in addition to radiotherapy, but indistinct is the precise regimen and the intensity along the radiotherapy. All efforts towards decreasing late side effects of treatment should be encouraged in this long life expected group.