International journal of pediatric otorhinolaryngology
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Int. J. Pediatr. Otorhinolaryngol. · Oct 2012
Randomized Controlled TrialTranexamic acid in adenotonsillectomy in children: a double-blind randomized clinical trial.
Adenotonsillectomy is one of the most common surgical procedures in pediatric otolaryngology, in which bleeding is a potential complication. We evaluated the efficacy of intravenous tranexamic acid in reducing intraoperative bleeding volume, and bleeding in the following 10 postoperative days in children who underwent adenotonsillectomy. ⋯ There is no benefit in the use of tranexamic acid for reducing bleeding during the transoperative period of adenotonsillectomy in children. More studies with a greater sample are required to evaluate the benefit of tranexamic acid in postoperative bleeding.
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Int. J. Pediatr. Otorhinolaryngol. · Oct 2012
Randomized Controlled TrialVasoconstrictive and analgesic efficacy of locally infiltrated levobupivacaine in tonsillectomy patients.
The use of preincisional plain levobupivacaine, lidocaine adrenaline and saline for perioperative blood loss and postoperative analgesia in pediatric tonsillectomy patients are compared. ⋯ Levobupivacaine has a vasoconstrictive effect in 0.25% concentrations that may be beneficial in tonsillectomy patients and has a consistent analgesic effect.