International journal of pediatric otorhinolaryngology
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Int. J. Pediatr. Otorhinolaryngol. · Jun 2016
Observational Study"Post intubation Laryngeal injuries in a pediatric intensive care unit of tertiary hospital in India: A Fibreoptic endoscopic study".
To identify acute laryngeal injuries among pediatric patients intubated for more than 48hours, and to correlate these injuries with clinical variables. ⋯ Post-extubation laryngeal injuries are not uncommon. Fiberoptic endoscopy is an inexpensive and cost-effective tool for bedside evaluation of post-intubation status in pediatric larynx. Early diagnosis of post-intubation laryngeal injuries in children can prevent long term sequelae. Hence, post-extubation fiberoptic laryngoscopy should be done routinely in pediatric population.
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Int. J. Pediatr. Otorhinolaryngol. · Jun 2016
Endotracheal tubes and the cricoid: Is there a good fit?
Choosing an appropriately sized endotracheal tube (ETT) is important in pediatric patients as an inappropriately sized ETT may result in multiple endotracheal intubation attempts or excessive pressure on the tracheal mucosa with the potential for airway damage. Although age-based formulas are generally used with choice of an ETT based on the internal diameter (ID), measurements of the outer diameter (OD) of the ETT would seem to be a more scientific approach to determine the proper size of an ETT. However, the variable OD of the ETT despite the same ID makes the selection of a proper sized ETT more difficult. The current study compares airway dimensions measured using computed tomography (CT) with the OD of ETTs from various manufacturers. ⋯ When choosing an ETT, age-based formulas which use the ID may not be uniformly accurate in ensuring the appropriately-sized ETT given the variation in the OD despite the same ID. These issues further support the use of cuffed ETTs as the variation in fit can be adjusted by inflation of the cuff to provide an adequate tracheal seal.
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Int. J. Pediatr. Otorhinolaryngol. · Jun 2016
Evaluation of the protective effects of hesperetin against cisplatin-induced ototoxicity in a rat animal model.
We aimed to investigate the effects of hesperetin as a flavanon both histopathologically and immunohistochemically on cochlear apoptosis in a rat model of cisplatin-induced ototoxicity (CIO). The evaluation of the effects of hesperetin on cisplatin-induced hearing loss was performed using distortion product otoacoustic emission (DPOAE). ⋯ Hesperetin may prevent ototoxicity by increased antioxidant enzymes and reduced oxidant parameters and protected against apoptosis resulting from a proliferation of cochlear cells in CIO.