AJNR. American journal of neuroradiology
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AJNR Am J Neuroradiol · Sep 1998
Case ReportsTraumatic subluxation of the globe into the maxillary sinus.
We report a case of complete traumatic subluxation of the globe into the maxillary sinus as documented by CT. The cornea sustained a mild epithelial abrasion but the globe was otherwise intact without signs of trauma.
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AJNR Am J Neuroradiol · Sep 1998
Comparative StudyNeurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats.
Results of a previous report showed that, if administered by intraventricular injection to access tissue normally protected by the blood-brain barrier, gadopentetate dimeglumine produced acute excitation, persistent ataxia, and widespread brain lesions in rats at 5-micromol/g brain but not at 3.8-micromol/g brain. The present study using gadodiamide was undertaken to see whether the effects were agent-specific. ⋯ The acute excitatory effects of high intraventricular doses of gadopentetate dimeglumine and gadodiamide are similar and appear to be attributable to local action at the infusion site, but differences exist between the two agents in the character and topography of the distant morphologic changes. The cerebellum was the brain area most sensitive to gadodiamide in this experimental model. It is unlikely that gadodiamide would gain access to the brain at these tissue doses when used intravenously for conventional clinical imaging, but our experimental model suggested that it had some unexpectedly specific neuropathologic potential.