AJNR. American journal of neuroradiology
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AJNR Am J Neuroradiol · Jan 2009
Clinical TrialIntra-arterial nicardipine infusion improves CT perfusion-measured cerebral blood flow in patients with subarachnoid hemorrhage-induced vasospasm.
Our aim was to determine the effects of intra-arterial (IA) nicardipine infusion on the cerebral hemodynamics of patients with aneurysmal subarachnoid hemorrhage (aSAH)-induced vasospasm by using first-pass quantitative cine CT perfusion (CTP). ⋯ IA nicardipine improves CBF and MTT in ischemic regions in patients with aSAH-induced vasospasm. Our data provide a tissue-level complement to the favorable effects of IA nicardipine reported on prior angiographic studies. CTP may provide a surrogate marker for monitoring the success of treatment strategies in patients with aSAH-induced vasospasm.
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AJNR Am J Neuroradiol · Jan 2009
Malignant fibrous histiocytoma of the head and neck: CT and MR imaging findings.
Malignant fibrous histiocytoma (MFH) is uncommon in the head and neck. The purpose of this study was to investigate CT and MR imaging features of 13 cases of MFH of this area. ⋯ Although rare, MFH of the head and neck is an aggressive tumor that arises most commonly in the sinonasal tract and is frequently associated with soft-tissue invasion and bone destruction on CT and MR images.
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AJNR Am J Neuroradiol · Jan 2009
Normal thickness and appearance of the prevertebral soft tissues on multidetector CT.
Analysis of the prevertebral soft tissue (PVST) is helpful in detecting osseous and ligamentous injuries of the cervical spine. Because the standard of care has shifted from radiographs to multidetector CT (MDCT), a re-examination of the PVST on MDCT images is needed to establish normal values for thickness appropriate for this imaging technique. ⋯ The thickness of the PVST is important in the detection of underlying injuries to the cervical spine. We propose the obtained values as the upper limits of normal for PVST thickness on MDCT images in the adult population.
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AJNR Am J Neuroradiol · Jan 2009
ReviewSusceptibility-weighted imaging: technical aspects and clinical applications, part 1.
Susceptibility-weighted imaging (SWI) is a new neuroimaging technique, which uses tissue magnetic susceptibility differences to generate a unique contrast, different from that of spin density, T1, T2, and T2*. In this review (the first of 2 parts), we present the technical background for SWI. ⋯ The use of SWI filtered phase as a means to visualize and potentially quantify iron in the brain is presented. Advice for the correct interpretation of SWI data is discussed, and a set of recommended sequence parameters for different field strengths is given.
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Very large and giant (> or =15 mm) cerebral aneurysms have a poor natural history, with high risk of subarachnoid hemorrhage or progressive symptoms of mass effect. Several endovascular techniques may be applied for treatment, depending on location, size, anatomy and presence of collateral circulation. The authors reviewed their clinical experience in endovascular treatment of 232 very large and giant aneurysms and present their perspective on the present state of the art in endovascular therapy for these aneurysms.