AJNR. American journal of neuroradiology
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AJNR Am J Neuroradiol · Oct 1998
Comparative Study Clinical TrialContrast-enhanced T1-weighted three-dimensional gradient-echo MR imaging of the whole spine for intradural tumor dissemination.
When evaluating intradural tumor dissemination in the spine, contrast-enhanced T1-weighted 2D spin-echo (2D-SE) images are frequently problematic because most of the lesions are very small. Our purpose was to compare 2D-SE images with 3D gradient-echo (3D-GE) postcontrast images to determine which technique is better for depicting intradural tumor dissemination. ⋯ The contrast-enhanced 3D-GE technique offers advantages over 2D-SE imaging in detecting intradural tumor dissemination, especially when the MPR technique is applied. This technique should be used for detecting intradural tumor dissemination.
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AJNR Am J Neuroradiol · Sep 1998
Case ReportsTraumatic subluxation of the globe into the maxillary sinus.
We report a case of complete traumatic subluxation of the globe into the maxillary sinus as documented by CT. The cornea sustained a mild epithelial abrasion but the globe was otherwise intact without signs of trauma.
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AJNR Am J Neuroradiol · Sep 1998
Comparative StudyNeurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats.
Results of a previous report showed that, if administered by intraventricular injection to access tissue normally protected by the blood-brain barrier, gadopentetate dimeglumine produced acute excitation, persistent ataxia, and widespread brain lesions in rats at 5-micromol/g brain but not at 3.8-micromol/g brain. The present study using gadodiamide was undertaken to see whether the effects were agent-specific. ⋯ The acute excitatory effects of high intraventricular doses of gadopentetate dimeglumine and gadodiamide are similar and appear to be attributable to local action at the infusion site, but differences exist between the two agents in the character and topography of the distant morphologic changes. The cerebellum was the brain area most sensitive to gadodiamide in this experimental model. It is unlikely that gadodiamide would gain access to the brain at these tissue doses when used intravenously for conventional clinical imaging, but our experimental model suggested that it had some unexpectedly specific neuropathologic potential.
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AJNR Am J Neuroradiol · Aug 1998
Comparative StudyCSF spaces in idiopathic normal pressure hydrocephalus: morphology and volumetry.
Idiopathic normal pressure hydrocephalus (NPH) is an important cause of dementia in the elderly; however, idiopathic NPH is often difficult to differentiate from normal aging and vascular dementias in which brain atrophy with ventricular dilatation (hydrocephalus ex vacuo or central atrophy) is present. To elucidate the distinctive features of the distribution of CSF in idiopathic NPH, we used MR imaging to investigate the morphologic features and volume of the CSF space in patients with idiopathic NPH compared with those with other dementias. ⋯ Our results indicate that findings of enlarged basal cisterns and sylvian fissures and of focally dilated sulci support, rather than exclude, the diagnosis of shunt-responsive idiopathic NPH and suggest that this condition is caused by a suprasylvian subarachnoid block.