Behavioural brain research
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Evidence from previous voxel-based morphometry (VBM) studies revealed that widespread brain regions are involved in chronic smoking. However, the spatial localization reported for gray matter (GM) abnormalities is heterogeneous. The aim of the present study was quantitatively to integrate studies on GM abnormalities observed in chronic smokers. ⋯ The convergent findings of this quantitative meta-analysis reveal a characteristic neuroanatomical pattern in chronic smokers. Future longitudinal studies should investigate whether this brain morphometric pattern can serve as a useful target and a prognostic marker for smoking intervention.