Medicine and science in sports and exercise
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Med Sci Sports Exerc · Sep 2012
Randomized Controlled Trial Multicenter StudyEfficacy and safety of diclofenac diethylamine 2.32% gel in acute ankle sprain.
Topical diclofenac diethylamine (DDEA) 2.32% gel achieves lasting efficacy in localized pain with two applications per day, while maintaining the favorable safety profile of topical diclofenac and potentially improving convenience and patient compliance. ⋯ DDEA 2.32% gel twice daily (applied in the morning and evening) was well tolerated and provided lasting relief from pain, improved function, and reduced symptomatic healing time in uncomplicated ankle sprain.