European heart journal
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European heart journal · Sep 2018
Randomized Controlled Trial Multicenter StudyBlood pressure, heart rate, and mortality in chronic obstructive pulmonary disease: the SUMMIT trial.
To characterize the relationship between blood pressure (BP) or heart rate and mortality and morbidity in chronic obstructive pulmonary disease (COPD). ⋯ A 'U-shaped' relationship between BP and all-cause mortality and cardiovascular events exists in patients with COPD and heightened cardiovascular risk. A linear relationship exists between heart rate and all-cause mortality and cardiovascular events in this population. These findings extend the prognostic importance of BP to this growing group of patients and raise concerns that both high and low BP may pose health risks.