Journal of tropical pediatrics
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Randomized Controlled Trial Clinical Trial
Room air vs. 100 per cent oxygen for neonatal resuscitation: a controlled clinical trial.
The aim of the study was to determine whether neonates resuscitated with room air compared with 100 per cent oxygen in the delivery room were less likely to have hypoxic ischemic encephalopathy and/or death before discharge. A controlled clinical trial was carried out at a tertiary care institute. All newborns weighing 1000 g or more with apnea or gasping respiration and/or heart rate less than 100 beats/min requiring positive pressure ventilation after initial steps of resuscitation were included. ⋯ The composite primary outcome occurred in 41.1 per cent of the neonates assigned to receive room air and 43.3 per cent of those in the 100 per cent oxygen group (odds ratio in the group assigned to room air, 0.92; 95 per cent confidence interval, 0.52-1.60). Resuscitation of a newborn baby with room air instead of the current practice of 100 per cent oxygen does not confer a benefit in terms of reduced HIE and/or mortality. Significantly, there is no increase in adverse outcome with the use of room air, which can be recommended for resuscitation if oxygen is not available.
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Neurocysticercosis is the most common parasitic infestation of the central nervous system which manifests commonly as acute onset focal seizures. We report a rare clinical presentation of neurocysticercosis in a 1-year-old infant who presented with involuntary movements. ⋯ Young children are rarely affected by this disease. In endemic areas, when a child presents with seizures or unusual neurological features and the CT scan shows contrast enhancing lesions or cystic lesions neurocysticercosis should be considered however young the child may be.