The Prostate
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Randomized Controlled Trial
Phase 3 clinical trial investigating the effect of selenium supplementation in men at high-risk for prostate cancer.
This study was conducted to investigate the effect of Se supplementation on prostate cancer incidence in men at high risk for prostate cancer. ⋯ Selenium supplementation appeared to have no effect on the incidence of prostate cancer in men at high risk. In conjunction with results of other studies, these data indicate that selenium supplementation may not have a role in prostate cancer chemoprevention.