La Revue de médecine interne
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Recent epidemiological study and clinico-pathologic data suggest overlaps between Alzheimer disease and cerebrovascular lesions that may magnify the effect of mild Alzheimer disease pathology and promote progression of cognitive decline. There is now strong epidemiologic evidence supporting an association between Alzheimer disease and two major vascular risk factors--blood pressure and diabetes. The major objective of this study is to analyse the impact of vascular risk factors on natural history of Alzheimer's disease. ⋯ The first data on vascular risk factors of the "Programme Hospitalier de Recherche Clinique: "Réseau sur la maladie d'Alzheimer français"" are the first step on comprehension of the impact of vascular risk factors and their traitments on Alzheimer's disease.
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The severe acute respiratory syndrome (SARS) has recently been recognised as a new clinical entity and a new emerging infectious disease that is highly contagious with significant mortality. ⋯ Research on specific therapies and vaccines is on-going.