La Revue de médecine interne
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HHV-8 is an oncogenic Gammaherpesvirinae discovered in 1994 during the HIV pandemic. It is the causative agent of Kaposi's sarcoma, and is also associated with the occurrence of several aggressive B lymphoproliferative disorders. Most of them occur in an immunosuppression setting, usually due to HIV infection. ⋯ Histology plays a key role in distinguishing these different entities and need expert reviewing, especially since they may be associated with each other. Besides lymphoproliferative disorders, HHV8 is associated with various hematological manifestations. The aim of this review is to provide an update on the presentation, diagnosis, and management of immunologic and hematologic complications associated with HHV-8.
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Case Reports
[Erythema nodosum due to cat-scratch-disease: An association and important therapeutic implications].
Cat-scratch disease is a zoonosis caused by Bartonella henselae and transmitted mostly through a break in the skin. This infectious disease is commonly characterized by a benign lymphadenitis. However, more unusual presentations have been observed. ⋯ Cat-scratch disease is an uncommon and poorly known cause of erythema nodosum, and must be systematically ruled out. As non-steroidal anti-inflammatory drug are usually prescribed as a treatment of erythema nodosum, it should be used cautiously to reduce the risk of complications in the cat-scratch disease.