La Revue de médecine interne
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Rev Med Interne
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Apremilast is a phosphodiesterase 4 inhibitor used in psoriasis and psoriatic arthritis Recently, this treatment has received marketing authorization for severe and refractory oral aphthosis in Behçet's disease. Idiopathic recurrent aphthous stomatitis (RAS) outside of Behçet's disease is often difficult to treat and can affect patients' quality of life. ⋯ Apremilast, which already has marketing authorization for Behçet's disease, also appears to be effective in RAS.