Fortschritte der Neurologie-Psychiatrie
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Fortschr Neurol Psychiatr · Dec 2005
Review[Recent advances in pathogenesis and therapy of multiple sclerosis].
In this article, recent advances in the research on pathogenesis and therapy of multiple sclerosis (MS) will be summarized. New evidence from clinical studies, imaging, histopathology and experimental models are discussed with a focus on neurodegenerative aspects and evidence from recent therapeutic studies. ⋯ The pathogenetic insights presented here may open new avenues for innovative immunomodulatory approaches and lead to an individualized MS therapy in the future. Neuroprotective treatment strategies aim at the protection of glial and neuronal cells.