Current eye research
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Current eye research · Feb 2012
Effects of supplemental erythropoietin on its receptor expression and signal transduction pathways in rat model of retinal detachment.
The aim of this study was to investigate the effects of supplemental erythropoietin (EPO) on its receptor (EPOR) and signal transduction pathways in rat model of retinal detachment (RD). ⋯ Supplementary EPO cannot affect EPOR expression in detached retina, but EPO may activate both PI-3K/Akt and MAPK/ERK-1/2 signal transduction pathways in RD model.