The Journal of asthma : official journal of the Association for the Care of Asthma
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Comparative Study
Cost-effectiveness of omalizumab for the treatment of inadequately controlled severe allergic asthma in Chinese children.
Objective: The addition of omalizumab to standard therapy has proven to be efficacious in children with severe allergic asthma. The goal of this study was to assess the cost-effectiveness of adding omalizumab to standard treatment for asthma in Chinese pediatric patients. Methods: A Markov model was constructed to project the health and economic outcomes in pediatric patients with severe allergic asthma. ⋯ Results: For the base-case analysis, the addition of omalizumab to standard therapy yielded an incremental cost of $49,047 for 0.232 incremental QALY, led to an incremental cost-effectiveness ratio of $211,217/QALY. Sensitivity analyses were robust for these results. Conclusions: This study found that the addition of omalizumab is not a cost-effective strategy compared with standard therapy for children with severe allergic asthma in China due to its high cost.