Kidney international
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Kidney international · Sep 2004
Multicenter StudyDuffy antigen receptor and genetic susceptibility of African Americans to acute rejection and delayed function.
The unique distribution of the alleles for the Duffy antigen receptor complex (DARC) that binds to chemokines may be associated with the rates of acute rejection and delayed allograft function (DGF) among African Americans. ⋯ The susceptibility of African American recipients to acute rejection and to DGF was not confirmed to be associated with DARC alleles or genotype. Future studies should exclude a potential role of donor-related DARC in transplant outcomes.