Journal of pediatric orthopedics
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Randomized Controlled Trial Multicenter Study
Botulinum toxin type A injection in alleviating postoperative pain and improving quality of life in lower extremity limb lengthening and deformity correction: a pilot study.
The Ilizarov technique is commonly used for lengthening and deformity corrections of the lower limbs in children. Postoperative pain can be significant, affecting quality of life and functional mobility, and often requiring prolonged medication use. Several studies have investigated the antinociceptive actions of botulinum toxin type A (BtX-A), yet evidence for its use in this population is limited. The objectives were to (1) establish the feasibility of a randomized clinical trial in children undergoing limb lengthening or deformity correction and (2) provide preliminary evidence of the beneficial effects of BtX-A in this population. ⋯ This pilot study established the feasibility of a randomized controlled trial design for in this population. Its findings indicate that BtX-A injections appear to be safe and effective for reducing pain and improving the quality of life and functional mobility of children undergoing lengthening or deformity corrections of the lower limbs. A larger-scale study is currently underway to confirm these preliminary findings.
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Radiographs can diagnose slipped capital femoral epiphysis (SCFE) on the anterior-posterior (AP) pelvis view and the frog-leg lateral view of the hips. On the AP radiograph, the lack of intersection between a line drawn parallel to the superior edge of the femoral neck (Klein's Line) and the epiphysis confirms a slip. Despite broad knowledge of the Klein's Line principle, application is difficult and inaccurate, especially in mild cases. On the frog-leg lateral radiograph, Southwick head/shaft angle and Wilson percent epiphyseal displacement commonly quantify the slip. Here, we set out to evaluate the intraobserver and interobserver reliability and the efficacy of these methods. ⋯ On the basis of our findings, head/shaft angle and percent epiphyseal displacement provide reliable and efficacious means of radiographic SCFE diagnosis. The classic definition of Klein's line fails to identify 60% of slips. We propose a modification of Klein's Line to improve sensitivity.
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The purpose of this study was to develop a triaging tool to predict pediatric in-hospital mortality from data available soon after emergency department (ED) presentation. ⋯ The risk of in-hospital mortality for injured children may be identified soon after arrival in the ED. This information may be used by frontline providers to appropriately triage patients to pediatric trauma centers quickly, to guide resuscitation, and for teaching purposes.