Journal of clinical psychopharmacology
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J Clin Psychopharmacol · Jun 2014
Randomized Controlled TrialThe effects of armodafinil on objective sleepiness and performance in a shift work disorder sample unselected for objective sleepiness.
Armodafinil is a medication used to treat excessive sleepiness in individuals with shift work disorder (SWD). In the present study, we investigate whether armodafinil can normalize nocturnal sleepiness in a group of typical SWD patients. ⋯ Armodafinil 150 mg administered at the beginning of a night shift normalizes nocturnal sleepiness in individuals with SWD unselected for objective sleepiness. Subjective measures of sleepiness and cognitive performance are also improved. This suggests that armodafinil can improve levels of nocturnal alertness to within normal daytime levels in the majority of patients with SWD.