Breast cancer research and treatment
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Breast Cancer Res. Treat. · Jun 2017
Mutational studies on single circulating tumor cells isolated from the blood of inflammatory breast cancer patients.
The molecular characterization of circulating tumor cells (CTCs) is critical to identify the key drivers of cancer metastasis and devising therapeutic approaches, particularly for inflammatory breast cancer (IBC) which is usually diagnosed at advance stages and progresses rapidly. ⋯ Our results indicate that CTCs could represent a non-invasive source of cancer cells from which to determine genetic markers as the disease progresses and identify potential therapeutic targets in IBC patients.