International journal of cardiology
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Multicenter Study Comparative Study
MR-pro-atrial natriuretic peptide (MR-proANP) predicts short- and long-term outcomes in respiratory tract infections: a prospective validation study.
Previous research found precursor levels of the atrial natriuretic peptide (MR-proANP) to be promising prognostic markers. This study aims to validate these findings and describe patterns of MR-proANP in a large cohort of patients with lower respiratory tract infections. ⋯ This study confirms the high prognostic performance of MR-proANP for short- and long-term mortality, particularly its high negative predictive value, in lower respiratory tract infections and community-acquired pneumonia, thereby complementing clinical risk assessment with the pneumonia severity index.