International journal of cardiology
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Meta Analysis Comparative Study
Dual versus single antiplatelet therapy after coronary artery bypass graft surgery: An updated meta-analysis.
The potential benefit and risks of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) in patients who undergo coronary artery bypass graft surgery (CABG) is controversial. ⋯ While DAPT has been associated with lower CV mortality in observational samples undergoing CABG, such findings were not replicated in RCTs. Lower rates of SVG occlusion with DAPT are offset by a higher rate of major bleeding.