Cephalalgia : an international journal of headache
-
Randomized Controlled Trial Multicenter Study
Efficacy and tolerability of rizatriptan for the treatment of acute migraine in sumatriptan non-responders.
The study was carried out to assess the efficacy and tolerability of rizatriptan orally disintegrating tablet (ODT) for treating acute migraine in patients who are non-responders to sumatriptan. ⋯ Rizatriptan 10-mg ODT was superior to placebo at providing two-hour pain relief and two-hour pain freedom in the treatment of acute migraine in those who do not respond to sumatriptan 100 mg. Rizatriptan was generally well tolerated in this population.