Cephalalgia : an international journal of headache
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Meta Analysis
Effectiveness of the progestin-only pill for migraine treatment in women: A systematic review and meta-analysis.
Background Migraine is highly prevalent in women (18%). Peak morbidity affects their most productive years, coinciding with peak fertility. Hormonal contraception is often tailored for migraine prevention. ⋯ Conclusions The desogestrel POP shows promise in improving migraine in women. Current evidence is observational and based on small samples of women using only one oral progestin-only formulation. Further randomized trials on additional progestin-only contraceptives are required to confirm their role in migraine management.