Nuclear medicine communications
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Clinical Trial
Reproducibility and normal ranges for gastric emptying in normal volunteers using a test meal designed for post-operative patients.
Scintigraphy is the current gold standard for the quantification of gastric emptying; however, results vary with meal composition. We modified a dual phase meal for administration to patients in the early post-operative period and aimed to test the reproducibility of the method, to obtain normal ranges and to compare these with previous data. Twenty healthy volunteers (10 male, 10 female), studied prospectively, were compared with 10 historical male volunteers. ⋯ Corresponding figures for the liquid phase were 33.2 min (26.1-40.3), 50.2 min (38.4-62.1) and 30.7 min (21.4-39.9). Bland-Altman plots for each phase showed good agreement between Tests 1 and 2 for Meal A. The modified test meal gave reproducible results in healthy volunteers; however, solid phase emptying was significantly faster than that of the bulkier test meal in historical subjects.