Nuclear medicine communications
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Accuracy of 18F-FDG PET-CT in triaging lung cancer patients with suspected brain metastases for MRI.
Brain metastases are common in lung cancer. Whole-body 2-deoxy-2-[fluorine-18]fluoro-D-glucose ([F]FDG) PET/computed tomography (CT) is used for general staging, but MRI is the best modality for characterizing brain abnormalities. We aimed to determine whether PET/CT is suitable for selecting patients for MRI on the suspicion of brain metastases. ⋯ The sensitivity of brain PET/CT for detecting brain metastases in lung cancer was above 70%, and the specificity was very high. Thus, PET/CT may be suitable for selecting patients for MRI in diagnostic centers that do not perform routine MRI in the pretherapeutic staging workup. The agreement among experienced readers was very high.