Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
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J. Oral Maxillofac. Surg. · Jan 2014
Randomized Controlled Trial Comparative StudyNicardipine infusion for hypotensive anesthesia during orthognathic surgery has protective effect on renal function.
Hypotensive anesthesia may adversely affect renal function. The purpose of this study was to evaluate the renoprotective effect of nicardipine in patients undergoing orthognathic surgery under hypotensive anesthesia. ⋯ Subclinical and reversible renal dysfunction appears during hypotensive anesthesia in patients undergoing orthognathic surgery. Continuous infusion of nicardipine attenuated the increase in NAG, which is a marker of renal tubular injury, during hypotensive anesthesia with desflurane and remifentanil.
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J. Oral Maxillofac. Surg. · Jan 2014
Comparative StudyEvaluation of reconstructive techniques for anterior and middle skull base defects following tumor ablation.
Reconstruction after resection of head and neck cancer can be challenging, especially when tumors extend to the base of the skull. Vascularized flaps are the option of choice, whether free or pedicled. Free flaps have the added benefit of access to the more cephalad defects of the anterior cranial base without the constraints of the rotation arc of pedicled flaps. The authors compared various flaps used for the reconstruction of defects of the anterior or middle skull base after resection of malignant tumors. ⋯ Vascularized flaps provide reliable and durable reconstructive options for anterior and middle skull base defects after resection of large complex malignant neoplasms of the craniofacial region. Free flaps, such as RFFFs, ALTs, and TDAPs, are well suited for these defects. They have a low risk of complications and low donor-site morbidity and offer good functional and esthetic outcomes.