American journal of clinical oncology
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Am. J. Clin. Oncol. · Oct 2007
Local recurrence after mastectomy in patients with T3pN0 breast carcinoma treated without postoperative radiation therapy.
The need for comprehensive adjuvant radiotherapy in patients with T3pN0 breast cancer is controversial. This retrospective analysis was performed to assess the frequency of local and distant recurrence in patients treated with mastectomy without postoperative radiation. ⋯ The risk of isolated local recurrence in patients with T3pN0 breast cancer and negative margins is moderately low and similar to T2pN0 patients. These results suggest that routine use of postoperative chest wall and nodal irradiation in all T3pN0 patients may not be required.