Clinical rheumatology
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Clinical rheumatology · Mar 2008
The assessment of cardiac functions by tissue Doppler-derived myocardial performance index in patients with Behcet's disease.
Vascular involvement is one of the major characteristics of Behcet's disease (BD). However, there are controversial findings regarding cardiac involvement in BD. Although early reports demonstrated that there is diastolic dysfunction in BD, conflicting results were found in the following trials. ⋯ There was statistically significant difference between the two groups regarding left ventricular MPI (0.458 +/- 0.072 vs 0.416 +/- 0.068%, p = 0.016), which were calculated from tissue Doppler systolic time intervals. There was also significant correlation between the disease duration and MPI (r = 0.38, p = 0.017). We have demonstrated that tissue Doppler-derived myocardial left ventricular relaxation time and MPI were impaired in BD patients, although systolic and diastolic function parameters were comparable in the patients and controls.
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Clinical rheumatology · Mar 2008
Case ReportsChorea as a side effect of gabapentin (Neurontin) in a patient with complex regional pain syndrome Type 1.
We report the case of a woman who developed chorea in her neck, trunk, and extremities soon after taking gabapentin as treatment for complex regional pain syndrome Type 1. The chorea lasted for a year and resolved completely within 2 weeks of discontinuing gabapentin.
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Clinical rheumatology · Mar 2008
Characteristic electron microscopic findings in the skin of patients with fibromyalgia--preliminary study.
This blinded study was done to determine if there are any abnormal electron microscopic (EM) findings in the skin of fibromyalgia syndrome (FMS) patients, which might contribute to or be due to the increased pain sensitivity seen in this condition. Skin biopsy samples were obtained from 13FMS patients and 5 control subjects. All tissues were prepared for EM examination by immediate prefixation in 2.5% glutaraldehyde for 2 h and postfixation in 1% osmium acid for 24 h. ⋯ Myelinated nerve fibers were unremarkable. The EM findings seen in the skin of FMS patients show unusual patterns of unmyelinated nerve fibers as well as associated Schwann cells. If these findings are replicated in a larger study, these abnormalities may contribute to, or be due to, the lower pain threshold seen in FMS patients.
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Clinical rheumatology · Mar 2008
Case ReportsSciatic nerve compression due to femoral neck osteochondroma: MDCT and MR findings.
A 34-year-old man presented with a 15-month history of pain along the left sciatic nerve. Radiographs and computed tomography (CT) revealed an exostosis on the postero-inferior aspect of the left femoral neck. ⋯ Although peroneal and ulnar neuropathies due to the compression by exostosis are reported frequently, imaging findings of sciatic nerve involvement were not well documented in the literature. Multidetector CT and MR findings of a sciatic nerve compression caused by a femoral neck exostosis were presented.