Clinical rheumatology
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Clinical rheumatology · Nov 2019
A preliminary study of lung abnormalities on HRCT in patients of rheumatoid arthritis-associated interstitial lung disease with progressive fibrosis.
This retrospective study evaluates lung abnormalities on high-resolution CT (HRCT) and clarifies which abnormality can predict the progressive fibrosis of rheumatoid arthritis (RA)-associated interstitial lung disease (ILD). ⋯ A wide distribution of subpleural RP and/or interlobular septal thickening and PBVI thickening on HRCT appear predictive of progressive fibrosis in RA-ILD. The combined evaluation of these two CT abnormalities has a good judgment value. Key Points • We designed this study to investigate the risk factors for progressive fibrosis in patients with RA-ILD. Factors including clinical, physiological, radiological and therapeutic variables were all included in the data analysis. • Our results showed HRCT abnormalities, rather than other parameters, appeared predictive of progressive fibrosis in RA-ILD. • The methods and results of image evaluation in this article would provide reference to rheumatologists in identifying early stage of progressive fibrosis which helps to improve poor prognosis of RA-ILD.
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Clinical rheumatology · Nov 2019
Mortality of patients with rheumatoid arthritis requiring intensive care: a single-center retrospective study.
Patients with rheumatoid arthritis (RA) are at a high risk for life-threatening conditions requiring admission to the intensive care unit (ICU), but the data regarding the outcomes of these patients is limited. The present study investigated the clinical characteristics and outcomes of RA patients admitted to an ICU. ⋯ Our study demonstrated a relatively high mortality rate among RA patients who were admitted to the general ICU. RA patients with risk factors such as heart failure, liver failure, elevated SOFA score, and vasopressor treatment in ICU should be promptly identified and treated accordingly. Key Points • The 30-day mortality rate of patients with RA that were admitted to the general ICU of a tertiary hospital was 34.9%. • The most common causes of ICU admission among patients with RA were infections and respiratory failure. Infections were the most common cause of death among these patients. • Patients with RA that present to the ICU with heart failure, liver failure, elevated SOFA score, and/or require vasopressor treatment in ICU should be promptly identified and treated accordingly.
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Clinical rheumatology · Nov 2019
Cross-cultural adaptation, validity, and reliability of the Turkish version of the Patient-Rated Elbow Evaluation.
The Patient-Rated Elbow Evaluation (PREE) is a joint-specific, self-administered outcome measure used to determine the level of pain and disability in patients with various elbow pathologies. The aim of this study was to cross-culturally adapt the PREE into Turkish (PREE-T) and to test its reliability and validity. ⋯ The Turkish version of the PREE is a valid and reliable outcome measure for assessing patients with elbow disorders. It is recommended to be used in research and clinical settings. Key Points • The Turkish version of the Patient-Rated Elbow Evaluation was successfully translated into Turkish and validated in a population with various elbow pathologies according to established guidelines • The Turkish version of the Patient-Rated Elbow Evaluation has high internal consistency and test-retest values • The Turkish version of the Patient-Rated Elbow Evaluation is valid and reliable.
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Clinical rheumatology · Nov 2019
Reliability and validity of Simplified Chinese version of Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) questionnaire: cross-cultural adaptation and validation.
To translate and cross-culturally adapt Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) Questionnaire into a Simplified Chinese version (QuickDASH-C), and evaluate the reliability and validity of the QuickDASH-C in patients with upper limb disorders. ⋯ • This study translated and cross-culturally adapted Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) questionnaire into a Simplified Chinese version. • The reliability and validity of Simplified Chinese version of QuickDASH were good in evaluating patients with upper limb disorders.
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Clinical rheumatology · Nov 2019
Multicenter StudyDoes symptomatic knee osteoarthritis increase the risk of all-cause mortality? Data from four international population-based longitudinal surveys of aging.
This study aimed at examining the association between symptomatic knee osteoarthritis and all-cause mortality based on four population-based longitudinal surveys. ⋯ In these four population-based longitudinal studies, no association between symptomatic knee osteoarthritis and increased risk of all-cause mortality was observed after adjusting for potential confounders. Key Points • This study evaluated the association between symptomatic knee OA and the risk of all-cause mortality among the participants retrieved from four large population-based longitudinal studies across the world. • No association between symptomatic knee osteoarthritis and increased risk of all-cause mortality was observed after considering potential confounders, and our findings were consistent with the results derived from four independent longitudinal studies. • The present study included four international population-based longitudinal studies, comprising both developed and developing areas, which allowed the findings to be interpreted under larger circumstance.