Journal of pediatric gastroenterology and nutrition
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J. Pediatr. Gastroenterol. Nutr. · Sep 2008
Compliance with gluten-free diet in children with coeliac disease.
Coeliac disease (CD) is a lifelong disorder with gluten-induced manifestations in different organs. Gluten-free diet (GFD) is required to achieve remission and prevent complications; however, study reports on GFD growth effect are not consistent. ⋯ Almost half of the coeliac patients were likely to abandon GFD without experiencing major symptoms, thus increasing the risk for developing complications later in life. An active attitude is required in the follow-up of patients with CD.
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Clinical trials use scientific methods to evaluate the effectiveness and safety of treatments or other interventions. Trials should have both internal and external validity, and a well-conducted randomised controlled trial is considered to be the most powerful tool for evaluating interventions. ⋯ In an internally valid trial, external validity refers to the ability of the results to be generalised to the "real world" population. Issues to consider in determining the external validity of a study include the setting of the trial, the study population, the types of interventions used, duration of follow-up, and the types of outcome and how they were assessed.
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J. Pediatr. Gastroenterol. Nutr. · Sep 2008
Pediatric gastroenterology fellows, class of 2007: how well are they prepared for the future?
Pediatric gastroenterology fellows are expected to acquire skills as clinicians, researchers, and educators. An e-mail survey was conducted to examine training experiences of individual fellows; to understand how graduating fellows rate their abilities as clinicians, researchers, and teachers; and to answer whether the size of a pediatric gastroenterology training program affects a fellow's training and future position choice. ⋯ The majority of fellows will pursue academic careers. Trainees may not be performing sufficient numbers of procedures. The number of procedures performed during fellowship was independent of program size.