Journal of pediatric gastroenterology and nutrition
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J. Pediatr. Gastroenterol. Nutr. · Jan 1983
Chronic diarrhea and neutropenia not associated with pancreatic insufficiency: a non-Shwachman-Diamond entity.
Six children with chronic diarrhea and neutropenia, initially referred for evaluation of Shwachman-Diamond syndrome, were found to have no evidence of pancreatic insufficiency. All presented in the spring with a prodromal respiratory illness. ⋯ The children were followed until growth returned to previous percentiles. Diarrhea and neutropenia resolved by 6-month follow-up, and there was no recurrence of the neutropenia at 1 year.
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J. Pediatr. Gastroenterol. Nutr. · Jan 1982
Randomized Controlled Trial Comparative Study Clinical TrialLubricant versus laxative in the treatment of chronic functional constipation of children: a comparative study.
The efficacy of two medications commonly used in treatment of chronic functional constipation of children (CFC) was compared. Thirty-seven children (aged 3-12 years) with typical CFC were assigned at random to treatment with mineral oil or standardized senna concentrate (Senokot). The results of follow-up evaluations at 1, 3, and greater than 6 months indicate that symptom control (fecal soiling and decreased stool frequency) was significantly better in mineral-oil-treated patients. ⋯ However, recurrences appeared later and less frequently in mineral-oil-treated patients. After 6 months, 55% of those treated with mineral oil had successfully discontinued regular medication. After 6 months, only 22% of Senokot-treated patients had successfully discontinued medication, while an additional 33% had stopped taking medication because of poor symptom control.