Journal of pediatric gastroenterology and nutrition
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J. Pediatr. Gastroenterol. Nutr. · Nov 2016
Randomized Controlled Trial Multicenter StudyFermented Milk Consumption and Common Infections in Children Attending Day-Care Centers: A Randomized Trial.
This multicenter, double-blind, randomized, placebo-controlled clinical trial investigated the effect of a fermented milk product containing the Lactobacillus casei National Collection of Microorganisms and Cell Cultures (CNCM) I-1518 strain on respiratory and gastrointestinal common infectious diseases (CIDs) in children attending day-care centers in Russia. ⋯ Although no other significant differences were shown between the fermented milk and control product groups in this study, lower incidence of rhinopharyngitis may indicate a beneficial effect of this fermented milk product.
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J. Pediatr. Gastroenterol. Nutr. · Apr 2016
Multicenter Study Comparative Study Observational StudySerum Vitamin D Depends Less on Latitude Than on Skin Color and Dietary Intake During Early Winter in Northern Europe.
To evaluate if dietary vitamin D intake is adequate for sufficient vitamin D status during early winter in children living in Sweden, irrespective of latitude or skin color. ⋯ Insufficient vitamin D status was common during early winter in children living in Sweden, particularly in those with dark skin. Although, higher dietary vitamin D intake in northern than southern Sweden attenuated the effects of latitude, a northern country of living combined with darker skin and vitamin D intake below recommendations are important risk factors for vitamin D insufficiency.
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J. Pediatr. Gastroenterol. Nutr. · Oct 2015
Randomized Controlled Trial Multicenter StudySafety of a New Amino Acid Formula in Infants Allergic to Cow's Milk and Intolerant to Hydrolysates.
Amino acid-based formulas (AAFs) are recommended for children with cow's-milk allergy (CMA) failing to respond to extensively hydrolysed formulas (eHFs). We evaluated the effects of a new thickened AAF (TAAF, Novalac), containing a pectin-based thickener, and a reference AAF (RAAF, Neocate) on allergy symptoms and safety, through blood biochemistry analysis and growth. ⋯ The new TAAF was tolerated by all of the infants with CMA and intolerance to eHFs. Anthropometric and clinical data showed that both formulas were safe.
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J. Pediatr. Gastroenterol. Nutr. · Jan 2015
Multicenter StudyNeuropsychological functioning and health-related quality of life: pediatric acute liver failure study group results.
Pediatric acute liver failure (PALF) is a rare but serious event, with poorly understood functional outcomes. The goal was to determine the prevalence of reduced neuropsychological functioning and health-related quality of life (HRQOL) following PALF. ⋯ Long-term PALF survivors demonstrate average IQ and visual spatial ability, but greater than expected impairments in motor skills, attention, executive function, HRQOL, and fatigue.
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J. Pediatr. Gastroenterol. Nutr. · Mar 2014
Multicenter Study Clinical TrialLubiprostone for the treatment of functional constipation in children.
Pediatric functional constipation is common; effective, easily administered treatment options are limited. Lubiprostone is an oral chloride channel protein-2 activator that stimulates gastrointestinal fluid secretion, softens stools, and facilitates bowel movements (BMs). We evaluated the safety and effectiveness of lubiprostone in children and adolescents with functional constipation. ⋯ Lubiprostone was efficacious and well tolerated in children and adolescents with functional constipation.