Regulatory toxicology and pharmacology : RTP
-
Regul. Toxicol. Pharmacol. · Jun 2002
Dermal absorption in rhesus monkeys of polychlorinated biphenyls from soil contaminated with Aroclor 1260.
Human health risk assessments involving contaminated soil include dermal absorption as a potential pathway contributing to the total exposure burden. For PCB-contaminated soil, the U. S. ⋯ The base soil used in the current study with Aroclor 1260 had an organic content of 5-6% (< or =2 mm particle fraction), a value typical for U. S. soil. The organic content of the soil applied to the skin was 8.7% (<150 microm particle fraction), a value that contrasts sharply with the soil containing 0.9% organics used in the 1993 study with Aroclors 1242 and 1254 that produced a dermal absorption value of 14% for PCBs.