Cornea
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To investigate changes in corneal topography and morphology in human eyes wearing orthokeratology (OK) lenses for overnight and over a 5-year period. ⋯ Short-term and long-term OK lens wear can effectively correct myopia by flattening the cornea. The flattened cornea in the short-term lens wear is mainly because of the thickening of the midperipheral cornea. In the long-term lens wear, however, this change is associated with thickening of the midperipheral cornea and thinning of the central corneal epithelium.