Neurologic clinics
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The classification of vasculitis and the clinical features of vasculitic neuropathy are reviewed. Vasculitic neuropathy usually presents with painful mononeuropathies or an asymmetric polyneuropathy of acute or subacute onset. ⋯ Steroids and cytotoxic agents have been the mainstay of therapy for most forms of vasculitic neuropathy. Dosing, potential side effects, and management recommendations of conventional therapies are provided.
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Diabetic neuropathies are the most common types of neuropathies worldwide. Although there has been significant progress in the understanding of the clinical aspects of these conditions, many questions remain unanswered or difficult to answer in terms of causation, risk factors and genetic susceptibility, effective treatments and restoration of nerve functions, and pain management. ⋯ Unfortunately and despite numerous drug trials, other than strict glycemic control, which is often difficult to maintain, there are no other treatments to slow the progression or delay the development of diabetic neuropathy. This article attempts to highlight a few unanswered or controversial questions regarding diabetic neuropathies.