Dermatologic clinics
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The use of nail care products and procedures to beautify and groom the nails is extremely common. Unfortunately, when improperly used, nail cosmetics can lead to nail diseases, such as paronychia, onycholysis, and brittle nails. Understanding the pathophysiology behind these conditions is an essential step toward better treatment and future prevention allowing patients to enjoy nail adornments while maintaining healthy nails.
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The neck has long been neglected when it comes to facial rejuvenation. More often than not the neck is left untreated, leaving the patient with a line of demarcation along the mandible separating a rejuvenated face from an aged neck. ⋯ Neck rejuvenation is usually performed in conjunction with facial rejuvenation, but can be an isolated procedure. Neck rejuvenation can be nonsurgical or surgical, with many options for combined approaches and modalities.
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Dermatologic clinics · Jul 2005
ReviewAdvances in the treatment of varicose veins: ambulatory phlebectomy, foam sclerotherapy, endovascular laser, and radiofrequency closure.
Several recent advances in the treatment of varicose veins have improved the safety, efficacy, comfort, efficiency, and long-term success of therapy. The advances of ambulatory phlebectomy, foam sclerotherapy, endovascular laser, and radiofrequency ablation with closure have made a significant positive impact on patient satisfaction. Duration of treatment and recovery is shorter, discomfort is minimized, and results are generally excellent. Studies assessing long-term outcomes are ongoing, and treatment modalities are continuing to evolve.
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Currently, use of standard antifungal therapies can be limited because of toxicity, low efficacy rates, and drug resistance. New formulations are being prepared to improve absorption and efficacy of some of these standard therapies. Various new antifungals have demonstrated therapeutic potential. ⋯ Heterogeneity in susceptibility of species to azole antifungals has been noted. This heterogeneity suggests that there are differences in activity of azoles, and different mechanisms of resistance to the azoles, which may explain the present lack of cross-resistance between some azoles despite apparent structural similarities. The mechanisms of azole action and resistance themselves are not well understood, and further studies into azole susceptibility patterns are required.
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V. vulnificus is an uncommon cause of soft tissue infection and primary septicemia, especially in patients with hepatic disease or who patients who are immunocompromised. The mortality of infection in these patients is extremely high despite timely antibiotic therapy. It is important to consider the possibility of infection with V. vulnificus in patients who present with high fever and rapidly progressive sepsis and have a history of consumption of raw seafood (especially oysters) or exposure of open wounds in a marine environment. Public education regarding the risk of raw seafood consumption is essential to preventing infection with this virulent pathogen.