Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Mar 2003
Randomized Controlled Trial Clinical TrialHeart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study.
The goal of this study was to assess the interaction between heart failure (HF) etiology and response to milrinone in decompensated HF. ⋯ Milrinone may have a bidirectional effect based on etiology in decompensated HF. Milrinone may be deleterious in ischemic HF, but neutral to beneficial in nonischemic cardiomyopathy.
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J. Am. Coll. Cardiol. · Mar 2003
Randomized Controlled Trial Comparative Study Clinical TrialA randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after the placement of coronary artery stents.
The aim of the present study was to compare clopidogrel and ticlopidine after coronary stenting with regard to cardiovascular death during long-term follow-up. ⋯ After the placement of coronary artery stents in unselected patients, ticlopidine was associated with a significantly lower mortality than clopidogrel. This raises concern about the current practice of substituting clopidogrel for ticlopidine after stenting and highlights the need for further long-term studies.
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J. Am. Coll. Cardiol. · Mar 2003
Comparative StudyDevelopment and validation of a simple risk score to predict the need for permanent pacing after cardiac valve surgery.
The study objective was to develop and validate a simple risk score to predict postoperative permanent pacing (PPM) after valve surgery. ⋯ A simple risk score incorporating preoperative conduction, age, prior valve surgery, and surgery type predicts PPM after valve surgery. This score may be useful in the perioperative management of valve surgery patients.
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J. Am. Coll. Cardiol. · Mar 2003
Comparative StudyPeak early diastolic mitral annulus velocity by tissue Doppler imaging adds independent and incremental prognostic value.
The aim of this study was to ascertain if left ventricular mitral annulus velocities measured by tissue Doppler imaging (TDI) are more powerful predictors of outcome compared with clinical data and standard Doppler-echocardiographic parameters. ⋯ Mitral annulus velocity measured by TDI in early diastole gives incremental predictive power for cardiac mortality compared to clinical data and standard echocardiographic measurements. This easily available measurement adds significant value in the clinical management of cardiac patients.