Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Nov 2006
Cardiovascular magnetic resonance, fibrosis, and prognosis in dilated cardiomyopathy.
We studied the prognostic implications of midwall fibrosis in dilated cardiomyopathy (DCM) in a prospective longitudinal study. ⋯ In DCM, midwall fibrosis determined by CMR is a predictor of the combined end point of all-cause mortality and cardiovascular hospitalization, which is independent of ventricular remodeling. In addition, midwall fibrosis by CMR predicts SCD/VT. This suggests a potential role for CMR in the risk stratification of patients with DCM, which may have value in determining the need for device therapy.
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J. Am. Coll. Cardiol. · Nov 2006
Comparative Study Clinical TrialGender-specific risk stratification with B-type natriuretic peptide levels in patients with acute dyspnea: insights from the B-type natriuretic peptide for acute shortness of breath evaluation study.
We examined whether B-type natriuretic peptide (BNP) levels allow gender-specific risk stratification in patients with acute dyspnea. ⋯ B-type natriuretic peptide plasma levels seem to be stronger predictors of death in women than in men.
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J. Am. Coll. Cardiol. · Nov 2006
Comparative StudyAdverse effects of dopamine on systemic hemodynamic status and oxygen transport in neonates after the Norwood procedure.
The purpose of this study was to evaluate the effects of dopamine on hemodynamic status and oxygen transport in neonates after the Norwood procedure. ⋯ Dopamine induces a significant increase in VO2 in neonates after the Norwood procedure, and termination is associated with an improved balance of VO2-DO2. These data further emphasize the importance of understanding changes in VO2 as well as DO2 in infants after cardiac surgery.