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Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Jan 2006
Randomized Controlled TrialAtorvastatin improves left ventricular systolic function and serum markers of inflammation in nonischemic heart failure.
This study examined the effect of statin therapy on vascular markers of inflammation and echocardiographic findings in patients with nonischemic forms of cardiomyopathy. ⋯ The use of atorvastatin in patients with nonischemic HF improves LVEF and attenuates adverse LV remodeling. The effects on soluble levels of several inflammatory markers with atorvastatin suggest, in part, mechanisms by which statins might exert their beneficial effects in nonischemic HF.