Journal of the American College of Cardiology
-
J. Am. Coll. Cardiol. · Oct 2008
Coenzyme Q10: an independent predictor of mortality in chronic heart failure.
The aim of this study was to investigate the relationship between plasma coenzyme Q(10) (CoQ(10)) and survival in patients with chronic heart failure (CHF). ⋯ Plasma CoQ(10) concentration was an independent predictor of mortality in this cohort. The CoQ(10) deficiency might be detrimental to the long-term prognosis of CHF, and there is a rationale for controlled intervention studies with CoQ(10).
-
J. Am. Coll. Cardiol. · Oct 2008
Meta AnalysisRelation of beta-blocker-induced heart rate lowering and cardioprotection in hypertension.
The purpose of this study was to evaluate the role of heart rate reduction with beta-blockers on the risk of cardiovascular events in patients with hypertension. ⋯ In contrast to patients with myocardial infarction and heart failure, beta-blocker-associated reduction in heart rate increased the risk of cardiovascular events and death for hypertensive patients.