Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Sep 2018
Randomized Controlled Trial Multicenter StudyCardiac Troponin I and Cardiovascular Risk in Patients With Chronic Obstructive Pulmonary Disease.
Patients with chronic obstructive pulmonary disease (COPD) have increased risk of cardiovascular events. ⋯ In patients with COPD and heightened cardiovascular risk, plasma cardiac troponin I concentrations are a specific and major indicator of future cardiovascular events and cardiovascular death. Inhaled therapies did not affect cardiac troponin I concentrations consistent with their neutral effect on mortality and cardiovascular outcomes. (Study to Evaluate the Effect of Fluticasone Furoate/Vilanterol on Survival in Subjects With Chronic Obstructive Pulmonary Disease [SUMMIT]; NCT01313676).